Functional Unit Representation Method (FURM)

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FURM is basic research. The project's goals are aggressive and even if it succeeds, it is likely to change drastically as we develop it. In addition, it is clear that there are many related research paths to be explored. Some of those paths involve the application of techniques that are successful in other disciplines (like fuzzy systems), some involve building bridges between seemingly incommensurate techniques (like between mathematical modeling and agent-based modeling), and some involving esoteric topics (like automata theory). As such, it's difficult to tell where it will end up or what might spin off of work being done on it.

However, the goals are clear enough to derive near- and medium-term objectives and requirements. The management of the project toward those objectives will follow the same philosophy as the FURM method, itself. It will be integrative, extensible, and open-ended. The point is not to dive down deep and develop any one technique, model, or technology. The point is to provide as much context and navigability to the practice of biological modeling as possible. This means pointing out and facilitating the relationships between the many different tools and methods used and discovered by biological modelers. The end result will be a web or network of techniques that improve the efficacy and efficiency of a modeling effort, regardless of the particular domain.

The current near-term objective is to use FURM (as it stands) to continue developing the ISL so that it can adequately account for, and possibly predict, the dynamics of the liver as it processes incoming blood. The milestones toward that objective consist primarily of building a mechanism for searching and analyzing the space of possible models of liver dynamics and structure (biotic and abiotic, healthy and diseased). If FURM can bring the ISL to this point, then it will have demonstrated its usefulness and feasibility.